Monitoring Anti-Tnf Drug Treatment in Inflammatory Bowel Disease. Is it Useful in Clinical Practice?
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چکیده
Submit Manuscript | http://medcraveonline.com Despite their efficacy, approximately 30% of patients do not respond to these therapies, and up to 40% of those who do respond lose efficacy over time [6]. To date, when faced with the failure to respond, the approach was to act empirically by intensifying the employed anti-TNF or by changing to another anti-TNF or a drug with a different therapeutic target. However, we need to find strategies that optimise these treatments, taking into account both the pharmacokinetics and pharmacodynamics [7,8].
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Utility of measuring serum concentrations of anti-TNF agents and anti-drug antibodies in inflammatory bowel disease.
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